Revisando el concepto de análisis por intención de tratamiento

Referencia: 

Johnston BC, Guyatt GH. Best (but oft-forgotten) practices: intention-to-treat, treatment adherence, and missing participant outcome data in the nutrition literature.Am J Clin Nutr. 2016;104(5):1197-1201. 

Author's comment: we address these issues with an emphasis on binary outcomes, and discuss how authors of randomized trials should address issues of both noncompliance and missing data.

Tamaño de muestra y...

... diferencia mínima clínicamente importante.

Referencia:

Jaeschke R, Singer J, Guyatt GH. Measurement of health status. Ascertaining the minimal clinically important difference. Control Clin Trials. 1989 ;10(4):407-15.